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"Compendium of Materia Medica" is a set of 16 centuries ago, the culmination of the Chinese herbal medicine works. The author is Li Ming, Zhuancheng in Wanli six years (1578), Wanli 23 years (1596) in Nanking (now Nanjing) official print and publish. From the "Compendium of Materia Medica" finalized to the marking, intermediate experienced ten years time, the reason was the "Compendium of Materia Medica" without the support of famous praise with the government, Li visited Qizhou, Huangzhou and Wuchang, printing can not be found booksellers. In 1579, he went to China was marking the publication of books in the center of Nanjing sought without success. In 1590, he finally got Nanjing bibliophile and publisher Hu Chenglong help pay for engraving. Unfortunately, Li's no time for three years they died at home, see his book published.
Li took about 27 years to modify their completion, "Compendium of Materia Medica", after three rewritten in Wanli six years (1578) was finalized. In this process, Li reference to more than 800 kinds of books, several field trips to the country, collecting samples, spent a very big effort.

"Compendium of Materia Medica" is Song Tang Shenwei of "Syndrome of Materia Medica" for the data subject Textual additions made. Qianlong thirty years (1765) essays drug experts Zhao Xuemin, "Compendium of Materia Medica", the intention in Supplements correction "Compendium of Materia Medica", which added 716 kinds of medicinal herbs, 161 kinds of medicines supplementary content, censure error 34.

"Compendium of Materia Medica" a total of 52 volumes, the drug 1892 kinds (of which 374 kinds of Li's new drugs), 1109 Figure book with drugs, prescription 11096 (of which more than 8000 are prepared and Li's own collection), about 190 million words, divided into 16 (water, fire, earth, stone, grass, grain, vegetables, fruit, wood, sERVER, insects, scales, rings, birds, animals, people) 60 class. Each drug breakdown Shiming (determine the name), Variorum (narrative origin), or false (correct mistakes of the past literature), Shuji (processing methods), smell, indications, invention (analysis refers to the first three drugs), With side (collect folklore prescription) other items. The book included 881 botanical species, 61 kinds of the appendix, a total of 942 kinds, plus 153 kinds of plants not to be named, a total of 1095 kinds, accounting for 58% of the total drug. Li, the plant is divided into five Grass, Valley department, the Department of vegetables, fruit portions, Kibe, again part of the grass mountain grass, grass, wet grass, poisonous weeds, overgrown grass, weeds, stone grass, moss grass, weeds and other nine categories.
influences

"Compendium of Materia Medica" to improve the traditional Chinese method of classification, more unified format, also described more scientific and accurate, such as: the generalized "worm" expanded to 106 kinds of drugs, including drugs insects 73 species, divided into "oviparous" "metaplasia" and "wet" into three categories [2]. Has great significance for the development of animal and plant taxonomy.

"Compendium of Materia Medica" corrected a lot wrong with the previous studies, such as the Southern Star and tiger palm, was originally the same drug, but mistaken past two drugs; luxuriantly before women wilt think the same drug, Lee through the identification confirmation of two; Su Song in "Maps of Materia Medica" smallpox, including building is divided into two, in fact, is the same plant; the previous misidentification "horse into the ground into a fine Cynomorium", "grass seed can become fish" eleven to correct it. In this book and also added a number of new drugs. The efficacy of certain drugs, Li also through their own experiences are further described. The book also contains a lot of valuable Syria and medical information, in addition to a large number of attached side, prescription and medical records governance experience, there are some useful historical medicine. Also Li and Chen refuted the possession of "Herbal Supplements" that cannibalism treatment Lei Zhai is wrong.

This book is not only a pharmacology book, or have a worldwide impact of natural history books, the contents of the book involves a very wide range, in biology, chemistry, astronomy, geography, geology, mining and even have some historical aspects of the contribution .